Family incidence of carcinoma of the colon and rectum in north-east Scotland
نویسندگان
چکیده
Family histories were obtained from 50 patients with adenocarcinoma of the colon or rectum in north-east Scotland. A comparable control group was similarly interviewed and in each group the case notes of the flrst degree relatives were studied where possible. Eight (16%) of the patients with cancer ofthe colon or rectum had a close relative with intestinal cancer compared with one (2%) of the control group. The patients with a positive family history of cancer of the large intestine did not have a higher proportion with adenomatous polyps nor were they younger than those patients with no such family history.
منابع مشابه
Carcinoma of the colon and rectum in North-East Scotland.
Family histories were obtained from 50 patients with adenocarcinoma of the colon or rectum in north-east Scotland. A comparable control group was similarly interviewed and in each group the case notes of the first degree relatives were studied where possible. Eight (16%) of the patients with cancer of the colon or rectum had a close relative with intestinal cancer compared with one (2%) of the ...
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4 Tchirkow GT, Lavery IC, Fazio VW. Crohn's disease in the elderly. Dis Colon Rectum 1983;26: 177-81. 5 Goligher JC. Crohn's disease (granulomatous enteritis). In: Goligher JC, de Dombal FT, Watts J McK. Surgery ofthe anus, rectum and colon. 4th ed. London: Bailliere, Tindall, 1980:827-57. 6 Kyle J. An epidemiological study of Crohn's disease in north east Scotland. Gastroenterology 1971 ;61:82...
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